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Two PhDs on a Pod: Daily Summaries Delivered
by Viome
Two PhDs on a Pod is where cutting-edge science meets real-world health. Hosted by Momo Vuyisich, PhD (Founding CSO of Viome) and Guru Banavar, PhD (Founding CTO of Viome), the podcast explores the intersection of biology, artificial intelligence, and personalized nutrition. Together, they break down the complex science behind how our bodies actually work—and what that means for living longer, healthier lives. Momo, a systems biologist, has focused on the biochemistry of the human body and the trillions of microbes that live within us. Guru, an AI and data science expert, develops computational systems that make sense of massive biological datasets. Together, they bring two complementary perspectives required to understand and translate the complexity of human biology and how it impacts health. Each episode will explain in simple terms the dynamic biology that makes each of us unique, and provide practical advice on how to apply these insights in daily life.
Latest Episodes
The most recent episodes — sign up to get AI-powered summaries of each one.
- 1 weeks ago1h 21m
Can Probiotics Protect Your Bones? Clinical Trial Evidence and the Science of Bone Health
Your bones are living tissue, and your gut has a say in how they hold up. Momo Vuyisich and Guru Banavar talk with Alicia Ballok, PhD, Discovery Director of Solaria Bio, about why bone loss is a silent epidemic, how microbial short-chain fatty acids calm inflammation and slow the cells that break bone down, and what a year-long trial in 286 women found. Plus: practical takeaways on DEXA scans, calcium, impact exercise and hormones, lentils, and a new study linking a gut-made fatty acid to artery health.
- 3 weeks ago1h 41m
AI Without the Hype: What’s Real, What’s Not, and How It Works
What does AI actually do well, and where does it fall apart? Momo Vuyisich, PhD, and Guru Banavar, PhD, start with a chest X-ray model that looked nearly perfect until it reached the clinic, then trace AI from 1980s expert systems to today's large language models and AlphaFold. You'll learn how machines learn, how statistics, machine learning, and AI differ, how diagnostic models are validated, the red flags to watch for in AI research claims, and where Guru thinks we are on the road to general AI.
- Sep 26, 20261h 12m
Therapeutic Plasma Exchange and the Science of Health & Longevity
Can removing something from your blood make you healthier? Emergency physician Dr. Brad Younggren joins hosts Momo Vuyisich, PhD, and Guru Banavar, PhD, to explain therapeutic plasma exchange: how it works, what the Circulate trial found across 35 biological aging clocks, what the AMBAR Alzheimer’s trial showed, why one session usually isn’t enough, and what we know (and don’t) about removing microplastics. Plus, gut bacteria that turn dietary choline into immune signals, and the promise and limits of multi-cancer blood tests.
- Sep 12, 20261h 27m
How Your Oral Health Affects Your Heart, Brain, and Overall Health
Everyone knows the Zuckerberg who built Facebook. But some know his father, Dr. Ed Zuckerberg, a dentist and technologist who joins hosts Momo Vuyisich and Guru Banavar to explore a different network: the one linking your mouth to your whole body. Learn how oral bacteria may influence the brain, heart, and metabolism, why microbial activity matters more than presence, and how saliva testing could reshape preventive care.
- Aug 27, 20261h 34m
Why We Need to Rethink How We Treat Chronic Disease
In this episode, Momo and Guru talk with Dr. Jeff Bland, a pioneer in functional medicine, who discusses the systemic approach to health, the importance of understanding root causes, and how personalized medicine is transforming healthcare. Learn how systems biology and innovative diagnostics are shaping the future of medicine.
- Aug 13, 20261h 11m
What the Most Measured Human Can Teach Us About Health
Dr. Michael Snyder of Stanford may be the most measured person in the world. He joins hosts Momo Vuyisich, PhD and Guru Banavar, PhD to explore what deep, continuous data reveals about our health — how he predicted his own diabetes, why microbial activity beats a list of microbes, how wearables can flag trouble before symptoms, and what a future of at-home measurement could look like. Plus food, hormones, and the science behind the latest health headlines.
- Jul 29, 20261h 9m
Gut Health PRO
Your gastroenterologist can spot a polyp, but what about the bloating, pain, and irregularity that fill most GI visits? Hosts Momo Vuyisich and Guru Banavar talk with gastroenterologist Dr. Michael Bass about Viome's Gut Health Pro: why measuring microbial activity (not just which bacteria are present) reveals what's actually driving symptoms, how food modulates the gut, and what the science says about treating the root cause instead of guessing.
- Jul 17, 20261h 5m
The Future of Medicine is AI
Entrepreneur and investor Vinod Khosla (co-founder of Sun Microsystems, founder of Khosla Ventures) joins Momo and Guru to explore how AI is reshaping medicine. Learn why expert medical knowledge is now nearly free, how daily engagement drives preventive health, why many supplement studies mislead, how AI reads molecular and microbiome data at scale, and what regulation and reimbursement must change. A candid look at personalized, preventive, and longevity medicine. Hosted by Momo Vuyisich, PhD and Guru Banavar, PhD.
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About Two PhDs on a Pod
Two PhDs on a Pod is where cutting-edge science meets real-world health. Hosted by Momo Vuyisich, PhD (Founding CSO of Viome) and Guru Banavar, PhD (Founding CTO of Viome), the podcast explores the intersection of biology, artificial intelligence, and personalized nutrition. Together, they break down the complex science behind how our bodies actually work—and what that means for living longer, healthier lives. Momo, a systems biologist, has focused on the biochemistry of the human body and the trillions of microbes that live within us. Guru, an AI and data science expert, develops computational systems that make sense of massive biological datasets. Together, they bring two complementary perspectives required to understand and translate the complexity of human biology and how it impacts health. Each episode will explain in simple terms the dynamic biology that makes each of us unique, and provide practical advice on how to apply these insights in daily life.
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