The Hunter Williams Podcast

IGF-1 Masterclass | A Complete Research Guide (2026)

October 13, 2026·1h 2m
Episode Description from the Publisher

Most people treat IGF-1 LR3 like a muscle peptide you just add to the cart. I want to slow that down a bit.In this masterclass I break down IGF-1 LR3 and IGF-1 DES. Both are modified versions of the IGF-1 your liver makes. They work by dodging the binding proteins that keep most of your IGF-1 parked and inactive. More free IGF-1 means more signal actually reaching the muscle.I cover who these make sense for and who should skip them. I walk through my dosing tiers, starting at 40 to 50 micrograms. We get into timing around training, why you always dose with carbs on board, and the day my wife and I ended up buying candy mid-workout.I also explain why your IGF-1 blood work might drop while you run these. Plus the feedback loop behind it, why I cycle four to six weeks, and how I stack them with TRT and growth hormone.One honest note. There are zero human trials on either compound. Most of the data comes from rats and cell cultures, and the rest is experience, mine included.Done right, these are a five to ten percent edge on top of a solid foundation. That’s it, and that’s still worth having.For research and entertainment purposes only. Subscribe for more peptide research and analysis.👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/links

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