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The BioHub - by Avetix: Daily Summaries Delivered
by Max Brennan - Biotech HeadHunter
Welcome to The BioHub, where the doors to the world of biotechnology swing wide open. Join your host, Max Brennan, a seasoned biotech recruiter, as he engages in thought-provoking conversations with the brightest minds in biotech. This podcast is your backstage pass to the insights, strategies, and stories that fuel success in the dynamic and ever-evolving biotech landscape. Get ready for an immersive experience into the world of biotech with The BioHub.
Latest Episodes
The most recent episodes — sign up to get AI-powered summaries of each one.
- 5 days ago16 min
Episode 253 - John Yu CEO at Kairos Pharma
In this episode of The BioHub Podcast, Ben is joined by Dr. John Yu, CEO and Chairman of Kairos Pharma, a clinical-stage biotechnology company developing innovative therapies to overcome drug resistance and immune suppression in cancer.Dr. Yu brings a unique perspective from his extensive career in neurosurgery, oncology, immunology, and biotechnology entrepreneurship. Together, they explore his journey from academic medicine into biotech leadership, the science behind Kairos Pharma's approach to tackling cancer drug resistance, and the development of its lead candidate, ENV105, which targets CD105 to potentially restore sensitivity to existing cancer treatments.The conversation also examines the challenges of translating academic discoveries into clinical therapies, building and financing an emerging biotechnology company, and the opportunities ahead for improving cancer treatment outcomes.An insightful discussion on scientific innovation, entrepreneurship, and the journey from breakthrough research to meaningful patient impact.
- 5 days ago25 min
Episode 252 - Sam Reich - CEO at SAB Bio
In this episode of The BioHub by Avetix, I’m joined by Sam Reich, CEO of SAB BIO.Sam shares his unconventional journey from leaving his PhD to build his first biotech, through founding and selling companies, working with influential industry figures like Phil Frost, and eventually leading Big Cypress Acquisition Corp.We discuss how that journey brought him to SAB BIO, why the company became the right opportunity, the challenges behind its strategic pivot towards type 1 diabetes, and what it takes to keep adapting when the path of a biotech changes.We also explore the lessons Sam has learned from building, financing and leading companies across multiple stages, and what comes next for SAB as it works to develop a disease-modifying treatment for type 1 diabetes.
- 1 weeks ago30 min
Episode 250 - Dr. Garry Pairaudeau, Co-Founder CEO & Dr. Anthony Bradley, Co-Founder CSO of Dalton Tx
In this episode of The BioHub, Amber is joined by Dr. Garry Pairaudeau, Co-Founder and CEO, and Dr. Anthony Bradley, Co-Founder and CSO of Dalton Tx.Having previously worked together at Exscientia, Garry and Anthony went on to co-found Dalton Tx. bringing together AI, scientific expertise and software engineering to help accelerate drug discovery.We explore their journey the challenges of translating advances in AI into meaningful scientific impact, and the importance of separating genuine innovation from industry hype.We also discuss the evolving role of AI in drug discovery, building a science-driven company, and what the future could hold for AI-enabled therapeutics.
- 1 weeks ago18 min
Why Biotech Keeps Reinventing the Wheel | Greg Crescenzi, Addgene
Why spend months recreating research tools that another lab has already built?In this episode of The BioHub, we’re joined by Greg Crescenzi from Addgene to discuss how sharing scientific materials can reduce duplicated work, save researchers time and help biotech discoveries move faster.From plasmids and CRISPR tools to viral vectors and antibodies, Greg explains how Addgene helps scientists build on existing research—and why improving access between academia and industry is the next challenge.We cover:• The frustration that sparked Addgene’s founding• How sharing research tools helped CRISPR reach thousands of organisations• The barriers between academic research and commercial biotech• Partnerships supporting better sequencing and new research tools• Why unsuccessful experiments contain information worth sharing• Where AI and Addgene’s research data could create new opportunitiesSubscribe to The BioHub for more conversations with the people advancing biotech.#Biotech #Addgene #CRISPR #BioHub
- 1 weeks ago27 min
Episode 248- Marshall Fordyce - Founder & CEO of Vera Therapeutics
In this episode of The BioHub by Avetix, I’m joined by Marshall Fordyce, Founder and CEO of Vera Therapeutics.Marshall shares his journey from medicine and HIV drug development at Gilead to founding Vera, and how that experience shaped his belief in the power of building medicines that can genuinely change the course of disease.We discuss what patient-centricity looks like in practice, the thinking behind Vera’s Phase III strategy, and the company’s transition from development-stage biotech into commercial launch. Marshall also shares his framework for building biotech companies, why people and capital discipline matter just as much as the science, and what comes next for Vera as it continues the US launch of Trutacna.
- 1 weeks ago24 min
Episode 247 - Chris Moxham Founder & CEO and Clayton Mellina CTO of Transcripta Bio
In this episode of The BioHub, Amber is joined by Dr. Chris Moxham, Co-founder and CEO of Transcripta Bio, and Clayton Mellina, CTO, to explore how transcriptomics and AI are opening up new possibilities in drug discovery.Chris and Clayton explain how Transcripta connects the changes disease causes in cells with the effects of potential treatments. They discuss combining phenotypic screening with target-based discovery, finding new uses for existing medicines, and reducing risk earlier in development.The conversation covers their work in genetically defined autism spectrum disorders and Huntington’s disease, their collaboration with Mayo Clinic, and how AI agents could help small scientific teams explore thousands of hypotheses.
- 1 weeks ago39 min
Episode 246 - Neil Warma - CEO, ProMIS Neurosciences
In this episode of The BioHub Podcast by Avetix, we welcome Neil Warma, President and CEO of ProMIS Neurosciences, a clinical-stage biotechnology company developing next-generation therapies targeting toxic, misfolded proteins associated with neurodegenerative diseases.Neil shares insights from his extensive career building and leading biotechnology companies, before exploring ProMIS' differentiated approach to treating Alzheimer's disease. We discuss PMN310, an antibody designed to selectively target toxic amyloid-beta oligomers while avoiding plaque, its ongoing Phase 1b PRECISE-AD clinical trial, and the potential to improve both efficacy and safety in Alzheimer's treatment.The conversation also explores ProMIS' broader ambitions across ALS and Parkinson's disease, upcoming clinical milestones, and Neil's perspective on leadership, financing, and building successful biotechnology companies.
- 2 weeks ago40 min
Episode 245 - Michael Fenn CBO Bexorg
On this episode of The BioHub, Amber Hayes is joined by Michael Fenn, Chief Business Officer at Bexorg, a precision neurology company combining AI with a pioneering whole-human brain platform to transform CNS drug discovery.Michael brings experience spanning biotech investing, business development and company building, including previous roles at Dewpoint Therapeutics and Iaso Ventures. He shares his journey across the industry, what attracted him to Bexorg, and why he believes the company’s approach could fundamentally change how neurological therapies are discovered and developed.We discuss the challenges of translating neuroscience research into effective treatments, how Bexorg is combining human brain pharmacology with AI to bridge the gap between preclinical research and clinical success, and the opportunities and challenges of building a platform-driven biotech.
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About The BioHub - by Avetix
Welcome to The BioHub, where the doors to the world of biotechnology swing wide open. Join your host, Max Brennan, a seasoned biotech recruiter, as he engages in thought-provoking conversations with the brightest minds in biotech. This podcast is your backstage pass to the insights, strategies, and stories that fuel success in the dynamic and ever-evolving biotech landscape. Get ready for an immersive experience into the world of biotech with The BioHub.
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