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Flex Diet Podcast: Daily Summaries Delivered
by Dr. Mike T Nelson
Dr. Mike T Nelson gets geeky with the latest research and scientific findings in the fitness world.
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- 1 weeks ago1h 24m
Do Fighters Really Need Zone 2? Heart Rate Recovery, Sprint Intervals & NIRS — James de Lacey — #410
James de Lacey is a strength and conditioning coach with an MSc in Sport & Exercise Science and more than a decade of experience in professional sport spanning professional and international rugby/rugby league. He now focuses on combat sports to prepare fighters under Sweet Science of Fighting.Do fighters really need zone 2 cardio? Strength and conditioning coach James de Lacey of Sweet Science of Fighting joins Dr. Mike T Nelson to challenge the "big aerobic base first" playbook for combat sports, from heart rate recovery and short-rest sprint intervals to muscle oxygen (NIRS) data. They also dig into VO2 max, wearables and why AI-written programs often miss the mark.Expect to learn why James questions the “huge aerobic base” approach for fighters, how heart rate recovery and heart rate kinetics can reveal more than time in zones, how short-rest sprint intervals and a simple air bike baseline test can guide programming, what muscle oxygen (NIRS) data can and can’t tell you, why trends beat single data points from wearables, and why generic AI-written programs often miss the mark—and much more.Connect with James:sweetscienceoffighting.comjamesdelacey.comSweet Science of Fighting on InstagramSweet Science of Fighting on YouTubeEpisodes you'll enjoy next:Episode 326: Row Hard, Breathe Easy: Boosting Aerobic Capacity with Dr. Kenneth Jay: Dr. Kenneth Jay on rowing and boosting aerobic capacity (Mike credits Dr. Jay for the bioenergetic testing he mentions in this conversation).Episode 221: Training performance, nitric oxide, blood flow, and more via the NNOXX device with Evan Peikon: Evan Peikon on training performance, nitric oxide and blood flow via the NNOXX device (Mike mentions Evan in this conversation).Episode Timestamps: 03:35 The biggest conditioning mistake in MMA05:50 Why sprints are more aerobic than you think07:46 Do fighters need a huge aerobic base?09:44 VO2 max, muscle limits and oxygen testing11:57 Conditioning trends and training volume15:36 Zone 2, time costs and the 80/20 debate22:10 Heart rate response and recovery between rounds25:43 Mike’s rower test and heart rate recovery28:25 Air bike sprints with short rests31:44 Muscle oxygen and power between repeats34:19 Testing and training each athlete’s limiter41:47 Flexible Meathead Cardio and technical training46:05 Elite athletes, VO2 max and training context50:22 NIRS, oxygen drops and peak power57:18 Why trends beat single test results1:02:56 Wearables, coaching judgment and session design1:06:57 AI programs and generic training blocks1:13:02 Training around life and where to find James Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter
- 2 weeks ago1h 27m
Will AI Replace Online Coaches? Peptides, TRT & Rower Cardio — Bryan Krahn — #409
Bryan Krahn has been a personal trainer since 1997, a CSCS since 2005, and a full-time online coach since 2014. He is a fitness writer and the author of two books with Men's Health.Will AI replace online coaches, or only the ones who stop being human? Veteran online coach and Men's Health author Bryan Krahn joins Dr. Mike T Nelson for a candid, unfiltered conversation about paying for expertise, whether coaches should disclose AI use, personal experiences with peptides and TRT (opinion, not advice), and Mike's simple rower-based cardio plan.Expect to learn why paying for expertise makes you a better coach, how Bryan and Mike use (and distrust) AI in coaching and writing, whether coaches should disclose their AI use, why stacking compounds makes personal experiments hard to interpret, how Bryan thinks about TRT and lab markers like HDL, LDL and PSA, and Mike’s simple rower-based cardio plan—and much more.Bryan and Mike discuss peptides, TRT and other compounds from personal experience and opinion. Nothing here is medical advice; talk to a qualified healthcare professional before changing any medication or supplement routine.Connect with Bryan:over50muscle.comBryan on Instagram (@bryankrahn)Episodes you'll enjoy next:Episode 137: Training Straight Talk with fitness writer, and online physique coach Bryan Krahn: Bryan's previous visit to the show: training straight talk from a fitness writer and online physique coach.AI Disclosure, Deepfakes & the Death of Expertise — Dean Guedo & Jeb Stuart Johnston — #404: Dean Guedo and Jeb Stuart Johnston on AI disclosure, deepfakes and the death of expertise (Mike mentions Dean in this conversation).Episode Timestamps:02:25 Online coaching's catch-22: taking clients you may not be set up to help04:16 Bryan's niche: from over-40 clients to the over-50 guy, and why parents and older dads fit06:10 Edge-case clients, referral networks and paying peers for expertise08:06 Why paying for consults still matters, including Bryan's 1999 consult with Charles Poliquin11:35 Why AI still struggles with niche training questions: PEDs, zone two and the Thomas Inch dumbbell17:03 AI inside coaching software, and why chatbots are so agreeable18:53 Would clients be accountable to a bot, and will live coaches last?23:48 Should coaches disclose AI use to clients? Everyday AI wins like soundbars and grill repair27:29 Contest-prep coaches, AI photo checks, and why coaches get second opinions34:32 Peptide offers and appetite-suppressing drugs: personal experiences, not advice39:38 DNP stories and risks as the speakers recount them42:34 Mitochondrial peptides, NAD+ and IV infusions: why stacked self-experiments are hard to interpret49:39 TRT: dialing in the basics first and working with a physician52:41 Lab markers: HDL, LDL and PSA, and changing the marker versus the outcome58:37 Traveling with a TRT prescription: Bryan's border-security story1:01:25 Mike's rower cardio plan: baseline 2K test, progressive six-minute sessions and a smarter four-by-four1:10:58 Should writers disclose AI use? Beating the blank page without losing your voice1:19:06 Wrap-up: coaching availability, training from 50 to 53, and where to find Bryan Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter
- 2 weeks ago1h 2m
Detox Beyond the Liver: Clearance Pathways & Body Burden with Dr. Gregory Kelly — #408
Dr. Gregory Kelly, N.D., is Chief Product Officer at Qualia Life, a naturopathic physician, author of Shape Shift, and former editor of Alternative Medicine Review.Detox is more than a liver story—and it is not a juice cleanse. Dr. Gregory Kelly of Qualia Life explains how clearance pathways work together, why mobilizing stored chemicals is not the same as eliminating them, and the thinking behind Qualia 2-Day Detox.Expect to learn why detox skepticism is warranted, how Dr. Kelly thinks about cumulative stress and chemical exposure, what liver biotransformation and elimination mean, why his formulation includes a between-meals binder stack, how sleep and the glymphatic system enter the conversation, and what Qualia’s small symptom-questionnaire study can and cannot establish—and much more.Dr. Kelly discusses his company’s Qualia 2-Day Detox product. Product descriptions and health claims are his views, not independent verification or medical advice; the small study discussed used self-reported symptom questionnaires.Connect with Greg:Qualia on FacebookQualia on InstagramQualia on TikTokDr. Gregory Kelly on LinkedInEpisodes you'll enjoy next:Episode 352: Dr. Dan Pardi on Stem Cells, Supplements, and the Future of Health with Qualia: Dr. Dan Pardi on stem cells, supplements, cognitive performance and health habits at Qualia.Episode 310: Unpacking the Science of Sleep with Dr. Allison Brager: Neuroscientist Dr. Allison Brager on sleep phases, circadian rhythms and performance.Episode Timestamps:05:03 Detox skepticism and why this conversation matters06:35 Why Qualia chose to develop a detox product, according to Dr. Kelly08:08 Who might need detox support, and Mike's experience with wildfire air pollution09:42 Dr. Kelly's environmental medicine background and the "last straw" bucket analogy for stress load12:44 Exposures Dr. Kelly tries to limit: canned foods, strong scents, new furniture, indoor air15:59 Small, consistent changes versus one silver bullet; Dr. Kelly cites biomonitoring studies18:59 Water filtration and drinking-water habits21:32 Larger exposures, the precautionary principle, mold, and skin products24:18 Sunscreen, sun exposure, and not overcomplicating health choices28:39 How Qualia approached the formulation, and an explanation of phase one, two, and three liver pathways33:07 Dr. Kelly's description of the four-step packets: morning and with-meal36:28 The between-meals binder stack, and a weight-loss study Dr. Kelly cites on stored chemicals40:26 The bedtime packet, the glymphatic system, and brain demands when learning new skills44:35 Fat-loss phases, a two-days-a-month approach, and Qualia's small symptom-questionnaire study48:49 Dr. Kelly's pairings for detox days: sauna, gentle movement, hydration, skin brushing, baths54:24 Wrap-up: fitting the routine into your schedule, and where to find more information Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter
- 3 weeks ago15 min
Beyond the Basics with Physiologic Flexibility: Certification Course is Now Open
In this episode of the Flex Diet Podcast, I break down why I built the Physiologic Flexibility Certification (PhysFlex) as a “level two” continuation after you’ve already got the basics of nutrition, training, and recovery mostly dialed in. I explain how Phys Flex targets four overlapping homeostatic regulators—temperature (heat/cold exposure), pH (acidity/alkalinity shifts), expanded fuels (ketones and lactate), and oxygen/CO2 regulation (breathing)—and why taking a systems view matters more than treating everything in silos. I share examples of how these pillars can become the real limiter in recovery and performance, including high-intensity work, long-duration events, and signs like elevated overnight respiration rate. Enrollment is open from Monday, October 12 through midnight PST Monday, October 19, 2026, and I’m offering direct email access for questions.Enroll here: https://physiologic.miketnelson.com/salesEpisode Timestamps:00:00 Welcome and Podcast Focus00:19 Course Enrollment Window01:44 Who This Certification Is For02:48 Why Four Pillars Together03:41 The Four Homeostatic Pillars05:05 Systems Thinking Over Silos08:07 Applying the Framework to Recovery11:41 Course Structure and Interventions13:09 Support, Email Access, Next Guest13:58 Medical Disclaimer and Closing Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter
- 4 weeks ago1h 30m
Strength Is a Skill: Sensory Training, the Nervous System & Neuroplasticity with Dr. Jordan Shallow — #407
Dr. Jordan Shallow, D.C., known as “The Muscle Doc,” is a chiropractor, strength and conditioning coach, and former competitive powerlifter. He is the founder of Pre-Script®, an education company that teaches coaches applied biomechanics and resistance training.Is getting stronger really about muscle, or about how well your nervous system learns the lift? Dr. Jordan Shallow, “The Muscle Doc,” explains why strength and size follow skill, how your senses shape movement, and how simple sensory inputs may change the way you train.Expect to learn when internal versus external cues make sense for strength and hypertrophy, how an intermediate lifter can use practice volume and frequency, why great lifters treat the empty bar like the heavy one, how touch, vibration, skin stretch and pressure may influence movement, and how neuroplasticity, lucid dreaming and film study connect to learning skills — and much more.Connect with Jordan:Website: themuscledoc.comPre-Script: pre-script.comInstagram: @the_muscle_docPre-Script on Instagram: @pre_scriptEpisodes you'll enjoy next:#401 — Psychedelics, Neuroplasticity and the Military-to-Spiritual Journey with Rick Alexander: A former Special Operations combat medic explains how a psychedelic experience reshaped his worldview, and what it taught him about neuroplasticity.#311 — Maximizing Athletic Performance with Neurology: Insights from Dr. Dylan Seeley: Dr. Dylan Seeley on how applying neurology can improve athletic performance.Episode Timestamps:03:47 Internal vs. external cues for strength and hypertrophy06:24 Longevity culture and why skill comes before loading09:58 Intermediate bench press case study: practice volume and frequency17:34 Ed Coan, intent and moving the empty bar like the heavy bar23:30 Sensory-motor savants: Tiger Woods, Nick Kyrgios and Brian Shaw27:29 How trainable is the sensory system?29:35 Foam rollers, kinesio tape and cupping through a neurological lens32:10 Perception, the electromagnetic spectrum and the limits of our senses36:23 Mechanoreceptors and vibration41:05 Light touch, vibration, skin stretch and deep pressure47:14 Fast feedback: testing and iterating with the nervous system51:38 Neuroplasticity, psychedelics and learning skills faster1:02:45 Reality Switch Technology, tropanes and perception1:05:08 Dreams, hypnagogic hallucinations and altered perception1:12:26 Lucid dreaming and practicing the deadlift without the load1:23:19 Film study, muscle memory and watching good reps1:26:37 Where to find Dr. Jordan Shallow Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter
- Sep 28, 20261h 2m
Is Zone 2 Overrated? HIIT, VO2 Max & Metabolic Flexibility with Dr. Martin Gibala — #405
Dr. Martin Gibala is a Professor of Kinesiology at McMaster University and one of the world's leading researchers on high-intensity interval training.Can short bursts of hard cardio outperform hours of Zone 2 for the average person? Exercise physiologist Dr. Martin Gibala explains how HIIT can improve VO2 max and metabolic flexibility, why elite athletes' 80/20 split may not fit a time-strapped schedule, and how to judge vigorous effort without chasing a perfect heart-rate zone.Expect to learn how to scale HIIT for beginners, what RPE and the talk test reveal about vigorous effort, when short sprints differ from VO2 max intervals, why elite athletes’ 80/20 approach may not fit your schedule, how Zone 2 definitions can mislead, and what metabolic flexibility and mitochondrial capacity really mean—and much more.Connect with Martin:Website: martingibala.comX: @gibalamBook: The One-Minute Workout (Avery, 2017; with Christopher Shulgan)Episodes you'll enjoy next:#402 — VO2 Max, Zone 2 Training & the Psychology of Human Performance — Ben Skutnik: Dr. Ben Skutnik cuts through Zone 2 hype and discusses VO2 max and aerobic-training evidence.#387 — Nathan T. Jenkins on Metabolic Flexibility, Aerobic Base, and First Principles: a look at aerobic development, energy systems, and repeated high-intensity performance.Episode Timestamps:2:25 Can beginners benefit from HIIT?4:20 Interval training basics and scaling effort7:13 Defining vigorous effort with RPE, heart rate, and the talk test11:32 Designing HIIT workouts around time and preference13:48 VO2 max intervals versus shorter sprints16:39 Moderate versus vigorous exercise: guidelines and time efficiency18:36 Is Zone 2 and the 80/20 rule right for everyone?22:50 Why Zone 2 definitions and wearables cause confusion29:12 Do you need an aerobic base before starting intervals?33:00 Why elite athlete training is not a blueprint for everyone35:22 What low-intensity volume may do for endurance athletes38:46 Double-threshold sessions, training stress, and recovery41:17 Carbohydrate intake and gut training in endurance sports44:31 Emerging recovery strategies and exogenous ketones49:12 Lactate supplementation: promise versus current evidence51:19 Fat max, metabolic flexibility, and mitochondrial capacity55:31 Exercise Science podcast and evidence over hype Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter
- Sep 21, 20261h 21m
Episode 405: Whole-Body MRI, CT Scans, and What Imaging Can Tell You — Matthew Paul Clemons, MD
Matthew Paul Clemons, MD, is a diagnostic radiologist specializing in nuclear medicine and body imaging. He is Head of Nuclear Medicine at Radiology Partners Houston and a rectal and prostate cancer specialist.Whole-body MRI promises a detailed look under the hood—but what can a quick screening scan actually see, miss, and send you chasing? Dr. Paul Clemons explains why a whole-body MRI is a limited study, how incidental findings can lead to further tests, and why standard screening remains the better choice for most people.Expect to learn how MRI creates images and why scan protocols take time, why open MRI systems can have important image-quality limits, how PET/MRI adds functional information, why CT and MRI can be complementary rather than redundant, how radiation and implanted devices factor into decisions, why spine findings do not always match symptoms, when conservative care deserves consideration, and where DEXA versus MRI can be useful for tracking body-composition trends.Episodes you'll enjoy next:#237 — Demystifying Body Composition Testing with Dr Grant Tinsley and Dr Eric Helms: a practical companion discussion on body-composition measurement and its limits.#159 — Advice, Mentorships, Askholes, and Diagnostics: An Interview with Dr. Adam Sumarski: a related conversation on diagnostics and imaging in sports medicine.Episode Timestamps:1:50 Whole-body MRI and preventive screening2:52 How MRI works: magnets, noise, and safety7:05 Open MRI, magnet strength, and image quality9:05 MRI sequences, scan time, and diagnostic protocols11:47 Why whole-body MRI is a limited screen12:46 Incidental findings and downstream testing13:57 High-risk screening, rare genetic conditions, and lung limits17:53 Sensitivity, specificity, and standard screening24:15 PET/MRI and where whole-body imaging has a clinical role27:05 Why MRI and PET/CT systems are expensive to install31:59 MRI safety, implants, and pacemakers36:36 CT versus MRI: why one scan can lead to another38:52 Whole-body CT, radiation, and its limits43:47 Back-pain scans: why an image may not explain symptoms51:44 Physical therapy, surgery, and warning signs58:46 Evaluating evidence for peptides, stem cells, and biologics1:05:47 Choosing an orthopedic surgeon for athletic goals1:15:24 DEXA versus MRI for body-composition trends Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter
- Sep 14, 20261h 19m
AI Disclosure, Deepfakes & the Death of Expertise — Dean Guedo & Jeb Stuart Johnston — #404
Dean Guedo is an Edmonton, Alberta-based online nutrition coach and strength/nutrition professional with roughly a decade in fitness, athletics and strength sports, and Jeb Stuart Johnston is a National Board Certified Health & Wellness Coach and the Charleston, SC-based founder of Food on the Mind, specializing in emotional eating and food obsession.Dean and Jeb join Dr. Mike T Nelson for their yearly AI check-in, getting into whether creators should disclose AI use and why deepfaked video is a very different beast than AI-assisted writing. The conversation ranges into dead internet theory, why so much hard-won fitness expertise never made it onto the internet at all, and why demanding physical skills may become more valuable, not less, as AI accelerates.Expect to learn whether creators should disclose their AI use and why deepfaked video is a fundamentally different risk category than AI-assisted writing, why LLM writing may have already "peaked" and regresses toward the average, why fitness's hard-won oral tradition (Charlie Francis, Louie Simmons, old forums) never made it onto the internet at all, why oral defense of your own thinking may be the most AI-proof skill you can build, and why demanding physical skills could become more valuable — not less — as AI accelerates, and much more.Connect with Dean:Instagram: @walk.more.kingWebsite: getfluxed.caConnect with Jeb:Website: foodonthemind.comInstagram: @jebstuartjohnstonNewsletter: Tangential, Inconsequential, Existential and Experiential (Substack)Episodes you'll enjoy next:Episode 136 — Flex Diet, Phys Flex, Metabolism and Nutrition Research for Compound Performance (Jeb and Dean interview Dr. Mike T Nelson): Listen hereS2 Ep 28 — High Flux Model and More for Fat Loss and Client Coaching, an interview with Dean Guedo and Jeb Johnston of StrongerU: Listen hereEpisode Timestamps:01:35 Welcome to the podcast & guest introductions03:15 Should you disclose your AI use?06:32 Deepfake video vs. AI-assisted writing: a different risk category07:53 AI's exponential growth and the "singularity" question11:11 What is "AI slop," and does it actually matter?12:42 Why LLMs regress toward average (and the Reddit problem)15:15 Falsely accused of "AI slop" for your own writing style21:36 "Automate your business with AI" — the wrong things to automate25:23 Dead internet theory: has AI writing already peaked?26:34 Why AI can't reason about truly novel, hypothetical situations28:37 Hemingway's unfinished-thought trick and "open-loop" thinking with AI35:06 Why weird, opinionated writing might be AI-proof44:49 Fitness's lost oral tradition: Charlie Francis, Louie Simmons, old forums47:03 Stoner, the trivium, and teaching without teaching48:06 Oral defense as the AI-proof assessment56:08 Research vs. coaching: the application gap (Norwegian 4x4, tabata)1:07:26 Will AI push us back toward hard physical skills?1:15:00 Where to find Jeb & Dean Get the Daily Fitness Insider newsletter (free): https://www.miketnelson.com/newsletter
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