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This Week in Virology: Daily Summaries Delivered
by Vincent Racaniello
TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.
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The most recent episodes — sign up to get AI-powered summaries of each one.
- 6 days ago1h 57m
TWiV 1369: Florida Model Makes Measles Great Again
TWiV explains projected effects of removing school-entry vaccination requirements on measles transmission in Florida and evidence that HLA class I escape drives the evolution of SARS-CoV-2 in human populations. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Effects of removing Florida school vaccination mandates (PNAS) HLA escape drives SARS-CoV-2 evolution (PNAS) The other landscape of SARS-CoV-2 evolution (PNAS) Letters read on TWiV 1369 Timestamps by Jolene Ramsey. Thanks! Picks of the Week Brianne – Astronomers Discover the First Green Star Rich – Inside the Johns Hopkins Psilocybin Playlist by Marc Shapiro (2020) Alan – The Wreck of the Mentor, by Eric Jay Dolin Vincent – The Apollo 11 Code is Open Source (and its' hilarious) Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
- 1 weeks ago54 min
TWiV 1368: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are discouraged by the continuous attack on vaccines especially the birth dose of the hepatitis B virus vaccine, effects of the 2026 changes in immunization schedule, the global burden of vaccine preventable diseases including pertussis and measles, expansion of the Bundibugyo ebolavirus outbreak in Kenya, increase in rabies diagnosis in the US and screwworm cases before Dr. Griffin deep dives into recent statistics RSV, influenza, SARS-CoV-2 infections, measles including an 8% increase in confirmed cases in 1 week in the US and its history especially the Faroe Island outbreak in 1846, warnings of congenital measles, effect of Fluvoxamine and Metformin to combat fatigue of long COVID and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Kennedy's Vaccine Plan Could Cause Surge in Hepatitis B, Study Finds(NY Times) Projected Effect of 2026 Federal Changes to the Childhood Immunization Schedule on Chronic Hepatitis B Virus Infections in the United States (Annals of Internal Medicine) Highlights from the Meeting of the Strategic Advisory Group of Experts (SAGE) on Immunization (WHO) The Effect of Pertussis Vaccination During Pregnancy on Pertussis and Diphtheria Immunity in Children at 3 and 4 Years of Age (JID) Effectiveness of Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine in Children Aged 6 Months–6 Years During a Statewide Pertussis Outbreak — Alaska, May–November 2024 (CDC: MMWR) Recommended Child and Adolescent Immunization Schedule for Ages 18 Years or Younger (AAP) Global, regional and national burden of pertussis in 1990–2023: a Global Burden of Disease study (Nature Medicine) Is Rabies Making a Comeback? (NY Times) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Epidemiological Alert: Myiasis caused by Cochliomyia hominivorax in the Americas Region, 16 October 2026 (PAHO) Ebola DRC (X) Ebola dashboard (ebola.fyi)
- 1 weeks ago1h 52m
TWiV 1367: Turning Off Hepatitis B Virus Without Cutting its DNA
TWiV explains a study which shows that influenza A virus infection induces immune dysregulation in the placenta and fetus without vertical transmission in nonhuman primates, and development of an epigenetic silencer therapy to transcriptionally inactivate viral DNA in chronic hepatitis B. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Helen Branswell, 69 (STAT) Influenza A virus and fetal immune dysregulation (Sci Adv) Epigenetic silencing for hepatitis B (Nat Biomed Eng) Letters read on TWiV 1367 Timestamps by Jolene Ramsey. Thanks! Picks of the Week Brianne – A healing touch for coral bleaching Kathy – Saturday Morning Physics especially The Science of Survey Research Rich – Everything is Tuberculosis by John Green Vincent – Death by Black Hole: And Other Cosmic Quandaries by Neil deGrasse Tyson Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
- 2 weeks ago1h 1m
TWiV 1366: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello are crestfallen to learn of the 6th measles death in Pennsylvania and more than 9000 deaths from Ebola, an enterovirus/Coxsackievirus outbreak at the University of Pennsylvania, decimation of the HIV services following withdrawal of PEPFAR and USAID, role of gut microbes in vaccine adverse events such as fever, continued raw milk consumption, and thermostable nanoparticles for mRNA vaccine delivery before Dr. Griffin deep dives into recent statistics RSV, influenza, SARS-CoV-2 infections, measles, development of a rapid diagnostic for measles, how long COVID effects sleep cycles and the microbiome, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Hand, foot, and mouth disease cases spike at Penn this fall (The Daily Pennsylvanian) HIV service delivery after the PEPFAR and USAID HIV funding withdrawal in Uganda and Zimbabwe: an interrupted time-series study (LANCET: Global Health) The human gut microbiome primes fever after vaccination (Science) Escape to 11,100' in Rustic Luxury (HaydenBackcountry) Consumption of Unpasteurized (Raw) Milk and Milk Products by Pregnant People and Children: Policy Statement (Pediatrics) Raw milk poses serious infection risks with no added health benefits, pediatrician group warns (CIDRAP) The Science and the Stakes of Raw Milk Consumption with Pam Ruegg, Nicole Martin, and Daniel Griffin (Dairy Digressions) First Birth Cohort Eligible for Chickenpox Vaccine Had a Sharp Drop in Shingles Cases (Epic Research) Accelerated discovery of thermostable mRNA–lipid nanoparticle vaccines using data-efficient AI (Nature: Biotechnology) Legionnaires' Disease (NYC: Health) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom) Ebola DRC (X) Ebola dashboard (ebola.fyi) EBOLA: The Democratic Republic of the Congo, 2026 (WHO) Bundibugyo virus disease outbreak Democratic Republic of the Congo(WHO: Democratic Republic of Congo) Ebola Outbreak: Current Situation (CDC:Ebola) Congo's Ebola infections <a h
- 2 weeks ago56 min
TWiV 1365: Andes Virus Up Close
TWiV travels to Porto, Portugal for the annual meeting of the European Society for Clinical Virology, where he speaks with Catherine and Corinne about their work on the Andes virus outbreak on the MV Hondius. Host: Vincent Racaniello Guests: Catherine Houlihan and Corinne Guerts van Kessel Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Transient Andes RNA detection in asymptomatic healthcare worker (Eurosurveill) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
- 3 weeks ago1h 14m
TWiV 1364: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss their continuing struggle to understand the ongoing outbreak of cyclospora, decimation of US public health including 30% or greater loss of personnel from the CDC, continuing measles outbreaks here and aboard, a mumps outbreak in San Diego and a Hib death in Montana, criminalization of pediatricians in Texas, dengue associated death in Florida, Ebola in Kenya, a new Legionnaires outbreak, screw worm cases, and a hearing in Florida to end requirements of four vaccines including Hib and chickenpox, before Dr. Griffin deep dives into recent statistics RSV, influenza, SARS-CoV-2 infections, the continued measles outbreak in Pennsylvania, US, Canada, statistics on vaccine preventable disease mortality in children, effectiveness of adjuvanted high dose influenza vaccine and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Smallpox History and Decisive Actions of George Washington (CDC: Emerging Infectious Diseases) Christina Jewett (NY Times) Caroline Hopkins Legaspi (NY Times) F.D.A. Found Cyclospora During Taylor Farms Inspection in Mexico (NY Times) Suspected plague incident leaves 1 dead, 200 under quarantine in Siberia (CIDRAP) Dozens quarantined in Siberia after plague institute lab worker dies (Reuters) Russia tells WHO there are no plague cases in Siberian city (Reuters) 30% effective workforce loss across CDC (AFGE Local 2883) CDC Leadership (CDC: About CDC) CDC Leadership 2025 (CDC) They Fought Outbreaks Worldwide. Now They're Fighting for New Lives. (NY Times) 'Zombified' C.D.C., Hobbled by Cuts, Struggles to Fulfill Scientific Mission(NY Times) San Diego State football hit by mumps outbreak with 14 confirmed cases ahead of Pac-12 opener (CBS Sports) Texas Pediatricians Face Paxton Investigations for Vaccinating Children (NY Times) Montana DPHHS reports pediatric death from complications of invasive Hib infection (NBC: Montana) Florida
- 3 weeks ago1h 53m
TWiV 1363: A Cauldron of Bats
TWiV explains a study testing how 16 hypothesized social and environmental drivers impact disease outbreaks, concluding that infectious disease spillover and emergence are multi-causal, and that no one-size-fits-all strategy can prevent epidemics and pandemics, and an analysis of Myotis bats, which shows that their remarkable longevity and immunity are linked through pleiotropic adaptations to viruses and aging-related disease. Hosts: Vincent Racaniello, Alan Dove, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Virus Appreciation Day (Day of the Year) Anthropogenic fingerprint on emerging infectious diseases (Nature) Longevity and virus-driven adaptations in Myotis bats (Nature) Letters read on TWiV 1363 Timestamps by Jolene Ramsey. Thanks! Picks of the Week Angela – Birds. Alan – Halloween t-shirts from my local animal shelter. Vincent – A Thousand Brains by Jeff Hawkins Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
- 4 weeks ago53 min
TWiV 1362: Clinical Update with Dr. Daniel Griffin
In his weekly clinical update, Daniel Griffin and Vincent Racaniello continue their ongoing exasperation over 5 deaths in Pennsylvania associated with measles infections, the absurdity of RFK Jr.'s statement that AI is better informed than physicians, the outbreak of cholera, more deaths by raw milk products, spread of dengue virus in Florida, Ebola in DRC, refusal to acknowledge the benefits of the HBV vaccine birth dose, how TORCH agent infections impact neurodevelopment and may lead to increase chances of autism diagnosis, Legionnaires disease and screw worm cases, before Dr. Griffin deep dives into recent statistics on RSV, influenza, SARS-CoV-2 infections, the continued measles outbreak in Pennsylvania, US, and Canada, modeling predictions of the outcome for repealing measles vaccination requirements to enter school in Florida, reactogenicity of different COVID vaccines and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode A.I. Is 'Better Informed' Than Doctors, Kennedy Tells Industry-Backed MAHA Summit (NY Times) WHO reports latest global trends in cholera, meningitis and plague (WHO) WHO: Global cholera deaths rose by 30% in2025 (CIDRAP) E. coli Outbreak Linked to Raw Milk Cheese (CDC: E. coli infection) CDC confirms multistate outbreak of E coli linked to raw milk cheese (CIDRAP) Dengue: Current Year Data (2026) (CDC: Dengue) Florida counties declare emergency over wildly unusual dengue outbreak (Washington Post) Critical role of hepatitis B birth dose vaccination in preventing mother-to-child transmission (CID) Effectiveness of timely hepatitis B birth dose vaccination to prevent mother-to-child transmission in Ethiopia (CID) Congenital TORCH Infections and Neurodevelopmental Outcomes (JAMA Pediatrics) Infections at birth substantially increase the risk of autism and intellectual disability, study finds (CIDRAP) UN Declaration on Pandemic Readiness May Head to General Assembly for Approval (Health Policy Watch) Legionnaires' Disease (NYC: Health) Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service) CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newro
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TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.
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