Systems Thinking and Beyond

Book Review: Building Ontologies with Basic Formal Ontology

September 10, 2026·24 min
Episode Description from the Publisher

The AI Team take a deep drive into a book that introduces applied ontology as a vital technical discipline designed to manage and integrate the massive amounts of data generated in modern biomedical science. The authors argue that information systems often suffer from interoperability issues caused by inconsistent terminology, technological silos, and logical errors known as imprecise thinking. To resolve these challenges, the book advocates for the use of Basic Formal Ontology (BFO), a top-level framework that provides a common set of categories for organizing scientific knowledge. By utilizing philosophical principles and structured logic, BFO helps developers create precise, computer-readable definitions that ensure data remains shareable and reusable across different research communities. Ultimately, the work serves as a guide for building robust information repositories that can support complex scientific reasoning and cross-disciplinary collaboration.

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